منابع مشابه
Cardiac Muscle
1. Cardiac muscle is a striated muscle, with a sarcomere structure much like that of skeletal muscle. It has small cells (as in smooth muscle), firmly connected end-to-end at the intercalated disks. 2. The action potential in cardiac muscle is long lasting compared to the duration of the contraction, preventing a tetanic contraction. 3. Under normal circumstances, cardiac muscle operates at len...
متن کاملThe cardiac muscle cell.
The cardiac myocyte is the most physically energetic cell in the body, contracting constantly, without tiring, 3 billion times or more in an average human lifespan. By coordinating its beating activity with that of its 3 billion neighbours in the main pump of the human heart, over 7,000 litres of blood are pumped per day, without conscious effort, along 100,000 miles of blood vessels. A detaile...
متن کاملCardiac Muscle Cells
The sarcoplasmic reticulum Ca2'-ATPase (SERCA2) plays a critical role in the contractile performance of cardiac and slow-twitch skeletal muscle by restoring cytosolic calcium to low resting levels during the contractile cycle. We have previously shown that SERCA2 expression in the heart is altered by a number of pathophysiological stimuli. In an effort to define molecular mechanisms regulating ...
متن کاملCardiac muscle involvement in muscle disorders.
Cardiac muscle involvement is not a rare complication in muscle disorders as is most commonlyseen in muscular dystrophies. Hypertrophic and/or dilated cardiomyopathy progresses in parallel with disease progression in most of patients with Duchenne and Becker muscular dystrophies, though cardiac failure mayprecede skeletal muscle symptoms, especially in Becker form. Cardiac muscle involvement is...
متن کاملMetabolism of Cardiac Muscle
Both pyruvate and lactate are extracted by the intact myocardium at physiological levels (1, 2) and are rapidly burned to CO2 in the intact cardiac muscle slice. They are interconverted by the diphosphopyridine nucleotide-dependent lactic acid dehydrogenase system and share a common final pathway for terminal oxidation (3, 4). Since these substrates are so closely related in carbohydrate metabo...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1968
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.36.3.497